British Fertility Society Statement on genetic imprinting disorder
in IVF Babies
16 January 2003
The British Fertility Society1 (BFS) understands the concerns of
patients regarding a recent UK study that has linked assisted conception
treatment to an increased risk of the genetic imprinting disorder,
Beckwith-Wiedemann syndrome. The BFS has examined the data in relation
to this genetic problem in detail and is committed to carefully
monitoring the consequences of treatments that we provide.
Beckwith-Wiedemann syndrome is a very rare condition. This form
normally affects only 1 in 30,000 babies. The study suggests that
after in vitro fertilisation treatment the chance of having a baby
with this condition is increased slightly to 4 in 30,000. Most of
these children are recognised as having problems at or soon after
birth, and the specific type of cancer that sufferers develop (Wilms
tumour) is unlikely to occur after the age of 4 years.
The chance of a child developing cancer before the age of 15 years
is 1 in 600 and about 80% of these cases are curable. We do not
have any evidence that the overall risk of cancer is increased after
assisted conception treatment.
The BFS is committed to providing safe treatments for couples who
are unable to have a family and will continue to work with researchers
to ensure that we achieve this aim.
1The British Fertility Society is a national multidisciplinary
organisation representing professionals practising in the field
of reproductive medicine.
For more information: please contact the British Fertility Society press office
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